The SRA domain: a connection between DNA methylation and histone modifications within the epigenetic code? The Arabidopsis VIM family.

Heterochromatin in both mammals and plants is associated with methylation of cytosines within the DNA sequence. While DNA methylation is widespread in plants, fungi, and animals, it has been curiously lost in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Caenorhabditis elegans, and Drosophila. However, the methylation system in Arabidopsis is very similar to that in mammals, showing that DNA methylation is highly conserved, and that Arabidopsis is an excellent model system to study it.

Short name and number: 
SRA AND EPIGENETICS (234849)
Name of US Partner: 
UNIVERSITY OF CALIFORNIA, LOS ANGELES
Contact: 

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) / ABAD RUIZ Carlos Manuel

Participating Countries: 
United States
Area: 

Health

Category: 

FP7 Project with U.S. partner