Single Particle Cryo-Electron Microscopy and Biophysical Characterization of Transient Receptor Potential Vanilloid 2 channel: a Three-Dimensional Structure Characterization of a Membrane Nociceptor.
The IOF call is a unique opportunity for the researcher to carry out this project. Transient Receptor Potential channels are extremely interesting since some of them are receptors for pain (nociceptors). The actual subject of research is the structural characterization of TRPV2, a nociceptor which responds to different stimuli such as cannabidiol, pressure and noxious heat. TRPV2 is expected to be a large membrane protein (potential homotetramer of ~400 KDa).
Short name and number:
Pain_TRPV2 (237120)
Name of US Partner:
The Brigham and Women's Hospital, Inc.
Contact:
UNIVERSITAT AUTONOMA DE BARCELONA (ES) / GONZALEZ MATOS Queralt
Participating Countries:
United States
Area:
Health
Category:
FP7 Project with U.S. partner
