Mobilising the enzymatic potential of hydrocarbonoclastic bacteria and the oleaginous yeast Yarrowia lipolytica to create a powerful cellular production platform for lipid-derived industrial materials

This proposal aims at developing a versatile fermentation platform for the conversion of lipid feed stocks into diverse added-value products. It is proposed to develop the oleaginous yeast Yarrowia lipolytica into a microbial factory by directing its versatile lipid metabolism towards the production of industrially valuable compounds like wax esters (WE), polyhydroxyalkanoates (PHA s), free hydroxyl fatty acids (HFA s) and isoprenoid-derived compounds (carotenoids, polyenic carotenoid ester).